Dipotassium Glycyrrhizinate: A Versatile Natural Compound for Skincare, Pharmaceuticals, and Functional Foods Dipotassium glycyrrhizinate is a premium-grade, white crystalline powder derived from the roots of licorice plants—specifically Glycyrrhiza uralensis Fisch. and Glycyrrhiza glabra L.—and offers a powerful blend of anti-inflammatory, antibacterial, soothing, and detoxifying properties. With a molecular formula of C42H60K2O16 and a CAS number of 68797-35-3, this compound has been scientifically validated for its efficacy in both clinical and cosmetic applications. Extracted using ethanol as a solvent, it demonstrates excellent water solubility, making it ideal for formulating high-performance products across multiple industries. Key Features: - High purity (98% HPLC) with stable chemical structure - Excellent aqueous solubility for easy integration into formulations - Naturally derived from licorice root extract, known for skin-soothing benefits - Mild, non-irritating profile suitable for sensitive skin types - Compatible with various product bases including creams, lotions, toothpaste, and beverages In-depth Description: This multifunctional ingredient acts as a potent anti-inflammatory agent by inhibiting key enzymes involved in inflammation pathways, such as phospholipase A2 and cyclooxygenase. Its ability to modulate immune responses makes it particularly effective in managing allergic reactions, redness, irritation, and even mild dermatitis. Unlike synthetic alternatives, dipotassium glycyrrhizinate provides gentle yet effective relief without compromising skin barrier integrity. It also exhibits antimicrobial activity against common pathogens like Staphylococcus aureus and Pseudomonas aeruginosa, enhancing product safety in personal care items. Additionally, its natural sweetness adds a subtle taste enhancement in food-grade applications while contributing to oral health through gingival protection. Application Scenarios: - Skin Care Formulations: Ideal for anti-redness serums, sensitive skin moisturizers, post-procedure recovery creams, and facial masks targeting inflammation and irritation. - Hair & Scalp Products: Supports hair follicle health, reduces scalp itchiness, and minimizes allergic reactions caused by harsh ingredients in shampoos or conditioners. - Oral Hygiene: Used in mouthwashes and toothpastes to reduce gum inflammation and promote oral comfort. - Baby Care: Safe for inclusion in baby powders and washes due to its low allergenic potential and calming effects on delicate skin. - Functional Beverages: Serves as a mild sweetener and anti-inflammatory additive in sports drinks and dietary supplements. Customer Testimonials: "Used in our new anti-redness serum—I've seen noticeable improvement in clients' reactive skin within two weeks." "Perfect for my natural toothpaste line—it enhances flavor and soothes gums effectively." "My baby's eczema-prone skin responded beautifully to the cream containing this ingredient—no more flare-ups!" Frequently Asked Questions: What is the recommended concentration for cosmetic use? For most skincare applications, concentrations between 0.1% and 0.4% are optimal depending on the formulation type—e.g., 0.1–0.2% for eye makeup, 0.2–0.4% for hair treatments, and 0.1–0.3% for facial lotions. Is it safe for sensitive or allergy-prone skin? Yes, dipotassium glycyrrhizinate is well-tolerated and commonly used in hypoallergenic products due to its anti-allergic and anti-inflammatory properties. How should it be stored? Keep in a cool, dry place away from direct sunlight to maintain stability and potency over time. Can it be used in food products? Yes, it meets regulatory standards for
Food Additives and can be incorporated into functional foods and beverages at levels up to 4.0209%, per current guidelines.
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