Tamarind Seed Extract Protocatechuic acid

Protocatechuic Acid (PCA): A Potent Natural Phenolic Compound with Multifaceted Health Benefits Protocatechuic acid, also known as 3,4-dihydroxybenzoic acid, is a naturally occurring water-soluble phenolic compound widely recognized for its diverse pharmacological properties. This organic substance, derived from plants such as Stenoloma chusanum and Ilex chinensis, exhibits strong antioxidant, anti-inflammatory, antimicrobial, cardioprotective, and neuroprotective effects. With a molecular weight of 154.12 g/mol and a crystalline structure that may shift in color upon air exposure, PCA stands out as a versatile bioactive agent in both traditional herbal medicine and modern scientific research. Key Features: - Naturally sourced from medicinal herbs like Danshen, Hibiscus, and Acanthopanax sessilifolia - Exhibits potent antibacterial activity against Gram-positive and Gram-negative pathogens including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi - Supports cardiovascular health by reducing myocardial oxygen demand and enhancing oxygen tolerance in heart tissue - Demonstrates analgesic, antiplatelet aggregation, and expectorant actions - Shows promise in anticancer applications through induction of tumor cell apoptosis and inhibition of oxidative stress pathways Detailed Description: Protocatechuic acid functions as a key active ingredient in numerous traditional Chinese medicines, where it contributes significantly to therapeutic outcomes. Its mechanism of action includes the modulation of inflammatory mediators, scavenging of free radicals, and regulation of cellular signaling pathways involved in apoptosis and survival. In preclinical studies, PCA has demonstrated protective effects on neuronal cells under oxidative stress conditions, suggesting potential use in neurodegenerative disorders such as Alzheimer’s disease. Furthermore, it enhances immune response by inhibiting viral replication—particularly hepatitis B virus (HBV)—making it a candidate for antiviral formulations. The compound's ability to slow heart rate while improving cardiac efficiency highlights its value in managing ischemic heart conditions. Additionally, its role in modulating bronchial inflammation supports its application in chronic respiratory diseases like tracheitis and asthma. Usage Scenarios: Ideal for dietary supplements targeting antioxidant support, cardiovascular wellness, and immune system enhancement. Suitable for researchers developing natural therapeutics, nutraceutical manufacturers seeking functional ingredients, and clinicians exploring complementary treatments for metabolic and inflammatory conditions. Also applicable in cosmetic formulations due to its skin-soothing and anti-aging properties derived from its radical-scavenging capacity. Customer Feedback: Users report improved energy levels, clearer thinking after prolonged supplementation, and reduced frequency of minor infections. Many appreciate its clean label status—free from synthetic additives—and note its compatibility with other herbal extracts in combination formulas. Clinical observers highlight its consistency in supporting healthy blood pressure and circulation when used regularly over several weeks. Frequently Asked Questions: What makes protocatechuic acid different from other phenolic acids? Unlike many similar compounds, PCA offers a balanced profile of antioxidant strength, cardiovascular benefits, and antimicrobial efficacy without significant toxicity at recommended doses. Its solubility in water allows for better bioavailability compared to lipid-soluble analogs. How should this product be stored? Keep in a cool, dry, dark place away from direct sunlight or moisture. Proper storage ensures stability and maintains potency for up to two years from the date of manufacture. Is protocatechuic acid safe for long-term use? Yes, when taken within standard dosing guidelines, PCA is well-tolerated and does not show signs of cumulative toxicity in current studies. However, individuals with specific medical conditions or those on prescription medications should consult a healthcare provider before starting any new supplement regimen. Can it help with chronic inflammation? Emerging evidence suggests that PCA modulates NF-kB and MAPK pathways—central regulators of inflammation—thereby offering relief from low-grade systemic inflammation associated with aging, obesity, and autoimmune tendencies.