
Angelica Dahurica Extract, also known as Bai Zhi Extract, is derived from the dried roots of Angelica dahurica. It is widely valued for its active compounds like imperatorin, offering benefits such as skin whitening, anti-inflammation, and respiratory support. Currently, it is in high demand in cosmetics, pharmaceuticals, and health supplements markets.
Our extract is sourced from premium-quality Angelica dahurica roots grown in Northern China, chosen for its rich soil and optimal growing conditions. The roots undergo careful harvesting and low-temperature water or ethanol extraction, ensuring high purity and bioactive stability.
The popular specifications include 10:1 ratio extracts and standardized imperatorin content, presenting as fine brown powders with mild herbal aromas and slightly bitter tastes. These are commonly used in skincare products (1-3% addition), pharmaceutical formulations (0.5-1.5g per serving), and health supplements (500-1000mg daily), delivering reliable efficacy and excellent solubility.
The Function of Angelica Dahurica Extract
1. Effect on the central nervous system
The effect of imperatorin on seizures was studied using the maximal electroconvulsive epileptic seizure threshold model in mice. The study found that intraperitoneal injection of 50 and 100 mg/kg-1 of imperatorin 30 minutes earlier could increase the voltage threshold of seizures in mice by 38% and 68%, respectively, and demonstrated that imperatorin improves mice with electrical stimulation. The effect of the onset threshold is dose and time dependent.
2. Effects on the cardiovascular system
The chromatographic retention peaks of imperatorin and verapamil were similar. It can reduce the protein content and cell volume of cardiomyocytes prestimulated by angiotensin I, and its effect is dose-dependent: the ratio of heart weight of spontaneously hypertensive rats treated with angiotensin I is significantly reduced, indicating that the effect of angiotensin I on both in vivo and in vitro is anti-hypertrophy.
3. Antibacterial and antiviral activity
Imperatorin has significant antibacterial and antiviral activity. Seven components were extracted from the flowers of Magydaris tomcntosa, and four components, including eucrutin, were tested for bacteriostasis. It was found that eucrutin had strong inhibitory activity against both gram-positive and gram-negative bacteria (minimum bacteriostasis concentration was 32-128 mg-ml).