2-octanoylaminoacetic acid CAS 14246-53-8 Capryloylglycine

Capryloylglycine: A Multifunctional Skincare Ingredient for Acne-Prone and Aging Skin Capryloylglycine is a powerful, skin-friendly amino acid derivative that has gained recognition in advanced cosmetic formulations for its ability to enhance product efficacy while delivering targeted benefits. This versatile ingredient combines antibacterial properties, sebum regulation, and anti-aging capabilities—making it an ideal component in creams, lotions, serums, and other skincare products designed for acne management, skin barrier support, and wrinkle reduction. Key Features: - High purity (>99%) with excellent stability - Odorless, bitter taste, white to off-white crystalline appearance - Soluble in oils, ethanol, propylene glycol, and 1,3-butanediol; nearly insoluble in water - Effective at low concentrations (0.2%–5.0%) in formulations - Compatible with pH levels between 3 and 8 - Ideal for oil phase incorporation during manufacturing Detailed Description: Capryloylglycine stands out due to its exceptional compatibility with human skin, enabling efficient delivery of active compounds such as antioxidants, peptides, and anti-inflammatory agents. Its molecular structure allows deep penetration into the stratum corneum, enhancing the bioavailability of co-formulated ingredients. Clinically, it demonstrates strong inhibition against Propionibacterium acnes and Staphylococcus aureus—two primary pathogens linked to inflammatory acne lesions. By reducing bacterial colonization and moderating sebum production, this ingredient helps prevent clogged pores and supports clearer, more balanced skin. Beyond its antimicrobial action, capryloylglycine plays a crucial role in maintaining youthful skin. It effectively suppresses elastase enzyme activity, which slows down the breakdown of elastin—a vital protein responsible for skin elasticity. As a result, regular use can lead to visible reductions in fine lines and wrinkles, particularly when incorporated into daily moisturizers or night treatments. Additionally, it contributes to pH balance restoration, supporting the skin’s natural protective barrier and improving self-repair mechanisms after environmental stressors like UV exposure or pollution. Ideal Applications: This ingredient is widely used in anti-acne formulas targeting mild to moderate acne vulgaris, especially those aiming for non-comedogenic, gentle cleansing without irritation. It also excels in anti-aging serums and nourishing creams where improved ingredient penetration and long-term skin resilience are priorities. Formulators often include it in facial cleansers, toners, gels, and spot treatments to provide both immediate and cumulative benefits over time. User Feedback: Users report smoother texture, reduced breakouts, and firmer skin after consistent application. Many appreciate how capryloylglycine enhances the performance of other actives like niacinamide, hyaluronic acid, and retinol—without causing sensitivity or dryness. Its mild formulation profile makes it suitable for sensitive and combination skin types seeking effective yet soothing solutions. Frequently Asked Questions: How does capryloylglycine differ from traditional antibacterial agents? Unlike harsh preservatives or alcohol-based sanitizers, capryloylglycine offers targeted microbial control with minimal disruption to the skin’s microbiome, making it ideal for daily use. Can it be used in vegan or clean beauty products? Yes, it meets modern standards for sustainable and ethical skincare, often found in certified clean beauty and cruelty-free formulations. Is it safe for all skin types? Absolutely—it's well-tolerated across various skin tones and conditions, including oily, acne-prone, and mature skin, provided it’s formulated within recommended dosage ranges. What is the best way to incorporate it into my product? Dissolve in the oil phase at 80°C before emulsification. Avoid high temperatures post-addition to preserve stability. Store sealed in aluminum packaging below 20°C away from light. In summary, capryloylglycine is a scientifically backed, multifunctional ingredient that bridges the gap between efficacy and safety in contemporary skincare. Whether you're developing professional-grade treatments or personal care routines, this compound delivers measurable improvements in clarity, texture, and firmness—with no compromise on gentleness.