Gram-positive bacillus, belonging to the Firmicutes phylum and Lactobacillus family, is slightly irregularly curved and rod-shaped, with a round tip.
Obligate heteromorphic fermentation bacteria metabolize sugars to produce lactic acid, acetic acid, ethanol and CO₂.
Distribution and planting
It is naturally present in the intestines, urinary tracts, skin and breast milk of most mammals and birds.
Strong adhesion: It binds to the intestinal mucosa through surface adhesives (such as mucin-binding protein MUB) to form a biofilm, which resists gastric acid and bile salts, achieving long-term colonization.
The modern carrying rate has dropped to 10-20% (30-40% in the 1960s), which is related to the reduction of fermented foods in the diet.
Digestive system diseases
Diarrhea and Infection
Reduce the severity of rotavirus diarrhea and shorten the course of the disease.
Inhibit the colonization of Helicobacter pylori (strain DSMZ 17648) and Clostridium difficile.
Irritable bowel syndrome (IBS) : Relieves abdominal pain and distension, and repairs the intestinal epithelial barrier.
Neonatal issues: Reduce the duration of colic crying, improve vomiting and reflux.
Immune and metabolic regulation
Anti-inflammatory: Inhibits Th1/Th2 overresponse through the "microbiota-inosine-adenosine A2A receptor" axis, reducing inflammation in multiple organs.
Lowering cholesterol: Strain NCIMB 30242 activates bile salt hydrolase and increases bile acid circulation.
Blood sugar regulation: The α -glucan produced delays starch digestion and improves insulin sensitivity.
Other potential benefits
Antiviral: Inhibits rotavirus, Coxsackievirus, etc.
Bone health: Alleviating bone loss caused by oophorectomy in animal experiments may be related to microbiota regulation.
Skin and hair: Case reports have shown improvements in skin luster and hair density, but the mechanism remains unclear.
