CAS 480-19-3 Sea Buckthorn Extract 99% Isorhamnetin

Isorhamnetin: A Potent Natural Flavonoid with Multifaceted Health Benefits Isorhamnetin, a naturally occurring flavonoid with the molecular formula C16H12O7, is derived from various medicinal plants such as ginkgo biloba and sea buckthorn. This bioactive compound has garnered increasing attention in scientific and wellness communities for its wide-ranging pharmacological properties, including antioxidant, anti-inflammatory, cardioprotective, hepatoprotective, and anti-tumor activities. As a dietary supplement or herbal extract, isorhamnetin supports holistic health by targeting oxidative stress, improving circulation, and enhancing metabolic function—making it an ideal choice for adults seeking natural support for cardiovascular, liver, and reproductive health. Key Features: - Clinically studied natural antioxidant that neutralizes free radicals - Enhances coronary artery dilation and blood flow efficiency - Inhibits platelet aggregation to reduce thrombosis risk - Supports healthy cholesterol metabolism in serum and hepatic tissues - Exhibits protective effects against chemical-induced liver damage - Modulates hormonal balance and male fertility parameters - Demonstrates anti-lipid peroxidation activity in vivo Detailed Description: Isorhamnetin functions at the cellular level by scavenging reactive oxygen species (ROS), thereby reducing oxidative stress—a primary contributor to aging and chronic disease. Its mechanism includes suppressing the formation of thiobarbituric acid reactive substances (TBARS), which are markers of lipid peroxidation in liver tissue. In addition to its antioxidant capacity, isorhamnetin acts as a vasodilator, promoting improved microcirculation and potentially lowering systolic pressure. Research also shows that this flavonoid interferes with platelet activation pathways, offering a non-pharmacological approach to maintaining healthy blood viscosity. For individuals concerned about liver detoxification, studies indicate that isorhamnetin mitigates hepatotoxicity induced by carbon tetrachloride (CCl4) and galactosamine (GalN)—two common toxins used in experimental models of liver injury. Moreover, emerging evidence suggests that isorhamnetin may influence reproductive physiology by regulating testosterone levels and spermatogenesis in animal models, positioning it as a promising candidate for male fertility enhancement. The compound’s ability to lower serum and hepatic cholesterol further underscores its role in metabolic health, particularly relevant in populations with elevated cardiovascular risk factors. Usage Scenarios: This versatile phytochemical is suitable for adults aged 18 and above who seek natural alternatives for: - Cardiovascular wellness, especially those experiencing mild hypertension or poor circulation - Liver support during periods of environmental toxin exposure or lifestyle-induced stress - Menstrual regulation in cases of stagnation-related amenorrhea - Digestive comfort following overindulgence or food stagnation - Anti-aging strategies focused on cellular protection and skin health - Immune modulation and general vitality maintenance Customer Testimonials: Users report improved energy levels, reduced fatigue, and clearer thinking after consistent use over several weeks. Many note enhanced recovery from physical exertion and better digestion without bloating. One long-term user mentioned that isorhamnetin helped manage occasional chest tightness associated with stress—a benefit attributed to its vasodilatory effect. Another shared how it supported menstrual regularity when combined with lifestyle adjustments, aligning with traditional uses in herbal medicine systems. Frequently Asked Questions: What makes isorhamnetin different from other antioxidants like quercetin or rutin? Unlike many flavonoids, isorhamnetin possesses unique structural features that enhance its bioavailability and specific interaction with cellular signaling pathways involved in inflammation and apoptosis. It also exhibits stronger inhibitory effects on certain enzymes linked to oxidative damage. Can isorhamnetin be taken alongside prescription medications? While generally safe, consult a healthcare provider before combining with anticoagulants, statins, or hormone-regulating therapies due to potential interactions with platelet aggregation and cholesterol metabolism pathways. Is it safe for daily consumption? Yes, when consumed within recommended dosages, isorhamnetin is well-tolerated. Most clinical trials have used doses ranging from 50–200 mg per day, typically showing no adverse effects in healthy adults. How soon can I expect results? Effects vary depending on individual health status, but many users notice subtle improvements in energy and digestion within 2–4 weeks of continuous use.